Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PIK3R3	HGNC:8981 (HGNC) 8503 (Entrez Gene) 606076 (OMIM) PIK3R3 (Alliance of Genome Resources)	Chr1 p34.1	Chr1:46040140-46174901 (-) GRCh38	colon adenocarcinoma	Q92569 (UniProt | EBI) NM_001114172 (RefSeq)
mouse	Pik3r3	MGI:109277 (MGI) 18710 (Entrez Gene) Gene Tree Pik3r3 (Alliance of Genome Resources)	Chr4 53.1 cM	Chr4:116078815-116160253 (+) GRCm39		ENSMUSG00000028698 (Ensembl Gene Model) ENSMUSP00000030464 (Ensembl) ENSMUST00000030464 (Ensembl)
rat	Pik3r3	RGD:621042 (Rat Genome Database) 60664 (Entrez Gene) Pik3r3 (Alliance of Genome Resources)	Chr5 q35			Q63789 (UniProt | EBI) NM_001429921 (RefSeq)
zebrafish	pik3r3a	ZDB-GENE-040426-1978 (Zebrafish Model Organism Database) 406311 (Entrez Gene) pik3r3a (Alliance of Genome Resources)	Chr2			NP_001278258 (RefSeq) NM_001291329 (RefSeq)
	pik3r3b	ZDB-GENE-040426-743 (Zebrafish Model Organism Database) 100000252 (Entrez Gene) pik3r3b (Alliance of Genome Resources)	Chr6			NP_957437 (RefSeq) NM_201143 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.