Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NUDT15	HGNC:23063 (HGNC) 55270 (Entrez Gene) 615792 (OMIM) NUDT15 (Alliance of Genome Resources)	Chr13 q14.2	Chr13:48037726-48052755 (+) GRCh38	thiopurine S-methyltransferase deficiency	Q9NV35 (UniProt | EBI) NM_018283 (RefSeq)
mouse	Nudt15	MGI:2443366 (MGI) 214254 (Entrez Gene) Gene Tree Nudt15 (Alliance of Genome Resources)	Chr14 39.06 cM	Chr14:73756320-73785682 (-) GRCm39	leukopenia neutropenia pancytopenia	214254 (NCBI Gene Model) Q8BG93 (UniProt | EBI) NM_172527 (RefSeq)
rat	Nudt15	RGD:1308292 (Rat Genome Database) 290365 (Entrez Gene) Nudt15 (Alliance of Genome Resources)	Chr15 q11			NP_001099519 (RefSeq) NM_001106049 (RefSeq)
zebrafish	nudt15	ZDB-GENE-040625-95 (Zebrafish Model Organism Database) 415197 (Entrez Gene) nudt15 (Alliance of Genome Resources)	Chr6			NP_001002107 (RefSeq) NM_001346166 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.