Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CEP290	HGNC:29021 (HGNC) 80184 (Entrez Gene) 610142 (OMIM) CEP290 (Alliance of Genome Resources)	Chr12 q21.32	Chr12:88049016-88142099 (-) GRCh38	Bardet-Biedl syndrome 14 Joubert syndrome 5 kidney disease Leber congenital amaurosis 10 Meckel syndrome 4 Senior-Loken syndrome	O15078 (UniProt | EBI) NM_025114 (RefSeq)
mouse	Cep290	MGI:2384917 (MGI) 216274 (Entrez Gene) Gene Tree Cep290 (Alliance of Genome Resources)	Chr10 51.48 cM	Chr10:100323410-100409527 (+) GRCm39	cystic kidney disease Joubert syndrome 5 Leber congenital amaurosis 10 visceral heterotaxy	216274 (NCBI Gene Model) Q6A078 (UniProt | EBI) NM_001400997 (RefSeq)
rat	Cep290	RGD:1311640 (Rat Genome Database) 314787 (Entrez Gene) Cep290 (Alliance of Genome Resources)	Chr7 q21			NP_001387932 (RefSeq) NM_001401003 (RefSeq)
zebrafish	cep290	ZDB-GENE-041111-243 (Zebrafish Model Organism Database) 560588 (Entrez Gene) cep290 (Alliance of Genome Resources)	Chr25			P85001 (UniProt | EBI) NM_001168267 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.