Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL4R	HGNC:6015 (HGNC) 3566 (Entrez Gene) 147781 (OMIM) IL4R (Alliance of Genome Resources)	Chr16 p12.1	Chr16:27313668-27364778 (+) GRCh38	acne allergic conjunctivitis asthma atopic dermatitis esophagitis interstitial lung disease multiple myeloma multiple sclerosis primary progressive multiple sclerosis renal cell carcinoma renal tuberculosis rheumatoid arthritis rhinitis	P24394 (UniProt | EBI) NM_001257406 (RefSeq)
mouse	Il4ra	MGI:105367 (MGI) 16190 (Entrez Gene) Gene Tree Il4ra (Alliance of Genome Resources)	Chr7 68.94 cM	Chr7:125151443-125178646 (+) GRCm39	asthma	16190 (NCBI Gene Model) P16382 (UniProt | EBI) NM_001363983 (RefSeq)
rat	Il4r	RGD:2899 (Rat Genome Database) 25084 (Entrez Gene) Il4r (Alliance of Genome Resources)	Chr1 q36			Q63257 (UniProt | EBI) NM_133380 (RefSeq)
zebrafish	il4r.1	ZDB-GENE-050227-5 (Zebrafish Model Organism Database) 503594 (Entrez Gene) il4r.1 (Alliance of Genome Resources)	Chr3			NP_001417771 (RefSeq) NM_001013282 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.