Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IRS3P	HGNC:6127 (HGNC) 442338 (Entrez Gene) IRS3P (Alliance of Genome Resources)	Chr7 q22.1	Chr7:100570131-100571401 (+) GRCh38
mouse	Irs3	MGI:1194882 (MGI) 16369 (Entrez Gene) Gene Tree Irs3 (Alliance of Genome Resources)	Chr5 76.59 cM	Chr5:137641294-137643976 (-) GRCm39		16369 (NCBI Gene Model) NP_034701 (RefSeq) NM_010571 (RefSeq)
rat	Irs3	RGD:69317 (Rat Genome Database) 84021 (Entrez Gene) Irs3 (Alliance of Genome Resources)	Chr12 q12			NP_114463 (RefSeq) NM_032074 (RefSeq)
zebrafish	si:ch73-335l21.1	ZDB-GENE-130530-591 (Zebrafish Model Organism Database) 794738 (Entrez Gene) si:ch73-335l21.1 (Alliance of Genome Resources)	Chr7			XP_021333440 (RefSeq)
	si:ch211-284e13.4	ZDB-GENE-060526-161 (Zebrafish Model Organism Database) 566919 (Entrez Gene) si:ch211-284e13.4 (Alliance of Genome Resources)	Chr5			XP_021327314 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.