Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	COL4A3	HGNC:2204 (HGNC) 1285 (Entrez Gene) 120070 (OMIM) COL4A3 (Alliance of Genome Resources)	Chr2 q36.3	Chr2:227164624-227314792 (+) GRCh38	Alport syndrome autosomal dominant Alport syndrome autosomal recessive Alport syndrome benign familial hematuria end stage renal disease	Q01955 (UniProt | EBI) NM_031363 (RefSeq)
mouse	Col4a3	MGI:104688 (MGI) 12828 (Entrez Gene) Gene Tree Col4a3 (Alliance of Genome Resources)	Chr1 42.32 cM	Chr1:82564647-82699778 (+) GRCm39	autosomal recessive Alport syndrome	12828 (NCBI Gene Model) Q9QZS0 (UniProt | EBI) NM_007734 (RefSeq)
rat	Col4a3	RGD:71085 (Rat Genome Database) 363265 (Entrez Gene) Col4a3 (Alliance of Genome Resources)	Chr9 q34			NP_001400917 (RefSeq) NM_001413988 (RefSeq)
zebrafish	col4a3	ZDB-GENE-070802-4 (Zebrafish Model Organism Database) 553354 (Entrez Gene) col4a3 (Alliance of Genome Resources)	Chr15			XP_694013 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.