Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TLCD4	HGNC:26477 (HGNC) 148534 (Entrez Gene) TLCD4 (Alliance of Genome Resources)	Chr1 p21.3	Chr1:95092517-95197607 (+) GRCh38		Q96MV1 (UniProt | EBI) NM_152487 (RefSeq)
mouse	Tlcd4	MGI:1923195 (MGI) 99887 (Entrez Gene) Gene Tree Tlcd4 (Alliance of Genome Resources)	Chr3 52.94 cM	Chr3:120995657-121076756 (-) GRCm39		99887 (NCBI Gene Model) Q8CGF5 (UniProt | EBI) NM_001355678 (RefSeq)
rat	Tlcd4	RGD:1563041 (Rat Genome Database) 365924 (Entrez Gene) Tlcd4 (Alliance of Genome Resources)	Chr2 q42			NP_001129351 (RefSeq) NM_001135879 (RefSeq)
zebrafish	si:dkey-10f21.4	ZDB-GENE-070912-350 (Zebrafish Model Organism Database) 100137126 (Entrez Gene) si:dkey-10f21.4 (Alliance of Genome Resources)	Chr2			NP_001108195 (RefSeq) NM_001114723 (RefSeq)
	tlcd4a	ZDB-GENE-090402-1 (Zebrafish Model Organism Database) 571836 (Entrez Gene) tlcd4a (Alliance of Genome Resources)	Chr24			XP_005162909 (RefSeq)
	tlcd4b	ZDB-GENE-041010-90 (Zebrafish Model Organism Database) 449652 (Entrez Gene) tlcd4b (Alliance of Genome Resources)	Chr3			Q5XIY2 (UniProt | EBI) NM_001362515 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.