Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PHC1	HGNC:3182 (HGNC) 1911 (Entrez Gene) 602978 (OMIM) PHC1 (Alliance of Genome Resources)	Chr12 p13.31	Chr12:8913843-8941467 (+) GRCh38	primary autosomal recessive microcephaly 11	P78364 (UniProt | EBI) NM_001413745 (RefSeq)
mouse	Phc1	MGI:103248 (MGI) 13619 (Entrez Gene) Gene Tree Phc1 (Alliance of Genome Resources)	Chr6 57.52 cM	Chr6:122294690-122317520 (-) GRCm39	dilated cardiomyopathy tetralogy of Fallot	ENSMUSG00000040669 (Ensembl Gene Model) ENSMUSP00000078514 (Ensembl) ENSMUST00000079560 (Ensembl)
rat	Phc1	RGD:1309203 (Rat Genome Database) 312690 (Entrez Gene) Phc1 (Alliance of Genome Resources)	Chr4 q42			NP_001101356 (RefSeq) NM_001107886 (RefSeq)
zebrafish	phc1	ZDB-GENE-081022-39 (Zebrafish Model Organism Database) 403008 (Entrez Gene) phc1 (Alliance of Genome Resources)	Chr16			NP_991270 (RefSeq) NM_205707 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.