Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	USP53	HGNC:29255 (HGNC) 54532 (Entrez Gene) 617431 (OMIM) USP53 (Alliance of Genome Resources)	Chr4 q26	Chr4:119212587-119295518 (+) GRCh38	progressive familial intrahepatic cholestasis	Q70EK8 (UniProt | EBI) NM_001389666 (RefSeq)
mouse	Usp53	MGI:2139607 (MGI) 99526 (Entrez Gene) Gene Tree Usp53 (Alliance of Genome Resources)	Chr3 53.75 cM	Chr3:122725142-122778159 (-) GRCm39		ENSMUSG00000039701 (Ensembl Gene Model) ENSMUSP00000087857 (Ensembl) ENSMUST00000090379 (Ensembl)
rat	Usp53	RGD:1306615 (Rat Genome Database) 295425 (Entrez Gene) Usp53 (Alliance of Genome Resources)	Chr2 q42			NP_001376197 (RefSeq) NM_001106468 (RefSeq)
zebrafish	usp53b	ZDB-GENE-090312-168 (Zebrafish Model Organism Database) 100537347 (Entrez Gene) usp53b (Alliance of Genome Resources)	Chr1			XP_005171014 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.