Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AP5Z1	HGNC:22197 (HGNC) 9907 (Entrez Gene) 613653 (OMIM) AP5Z1 (Alliance of Genome Resources)	Chr7 p22.1	Chr7:4775615-4794397 (+) GRCh38	hereditary spastic paraplegia hereditary spastic paraplegia 48	O43299 (UniProt | EBI) NM_014855 (RefSeq)
mouse	Ap5z1	MGI:1924908 (MGI) 231855 (Entrez Gene) Gene Tree Ap5z1 (Alliance of Genome Resources)	Chr5 81.53 cM	Chr5:142449699-142464465 (+) GRCm39	hereditary spastic paraplegia 48	ENSMUSG00000039623 (Ensembl Gene Model) ENSMUSP00000041863 (Ensembl) ENSMUST00000038699 (Ensembl)
rat	Ap5z1	RGD:1593125 (Rat Genome Database) 641386 (Entrez Gene) Ap5z1 (Alliance of Genome Resources)	Chr12 q11			NP_001032297 (RefSeq) NM_001037220 (RefSeq)
zebrafish	ap5z1	ZDB-GENE-120508-2 (Zebrafish Model Organism Database) 100537934 (Entrez Gene) ap5z1 (Alliance of Genome Resources)	Chr3			NP_001315060 (RefSeq) NM_001328131 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.