Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NAGS	HGNC:17996 (HGNC) 162417 (Entrez Gene) 608300 (OMIM) NAGS (Alliance of Genome Resources)	Chr17 q21.31	Chr17:44004622-44009068 (+) GRCh38	amino acid metabolic disorder N-acetylglutamate synthase deficiency	Q8N159 (UniProt | EBI) NM_153006 (RefSeq)
mouse	Nags	MGI:2387600 (MGI) 217214 (Entrez Gene) Gene Tree Nags (Alliance of Genome Resources)	Chr11 65.48 cM	Chr11:102036339-102040303 (+) GRCm39		ENSMUSG00000048217 (Ensembl Gene Model) ENSMUSP00000050258 (Ensembl) ENSMUST00000055409 (Ensembl)
rat	Nags	RGD:1565783 (Rat Genome Database) 303563 (Entrez Gene) Nags (Alliance of Genome Resources)	Chr10 q32.1			NP_001100523 (RefSeq) NM_001107053 (RefSeq)
zebrafish	nags	ZDB-GENE-121219-2 (Zebrafish Model Organism Database) 557716 (Entrez Gene) nags (Alliance of Genome Resources)	Chr3			E7FCP8 (UniProt | EBI) NM_001423779 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.