Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ALAS2	HGNC:397 (HGNC) 212 (Entrez Gene) 301300 (OMIM) ALAS2 (Alliance of Genome Resources)	ChrX p11.21	ChrX:55009055-55030977 (-) GRCh38	cutaneous porphyria erythropoietic protoporphyria hemochromatosis sideroblastic anemia sideroblastic anemia 1	P22557 (UniProt | EBI) NM_001037968 (RefSeq)
mouse	Alas2	MGI:87990 (MGI) 11656 (Entrez Gene) Gene Tree Alas2 (Alliance of Genome Resources)	ChrX 68.46 cM	ChrX:149330443-149353614 (+) GRCm39		11656 (NCBI Gene Model) P08680 (UniProt | EBI) NM_001409472 (RefSeq)
rat	Alas2	RGD:2084 (Rat Genome Database) 25748 (Entrez Gene) Alas2 (Alliance of Genome Resources)	ChrX			Q63147 (UniProt | EBI) NM_013197 (RefSeq)
zebrafish	alas2	ZDB-GENE-001229-1 (Zebrafish Model Organism Database) 64607 (Entrez Gene) alas2 (Alliance of Genome Resources)	Chr8			Q9YHT4 (UniProt | EBI) NM_131682 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.