Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SMC3	HGNC:2468 (HGNC) 9126 (Entrez Gene) 606062 (OMIM) SMC3 (Alliance of Genome Resources)	Chr10 q25.2	Chr10:110567684-110606048 (+) GRCh38	Cornelia de Lange syndrome 3 hepatocellular carcinoma intellectual disability	Q9UQE7 (UniProt | EBI) NM_005445 (RefSeq)
mouse	Smc3	MGI:1339795 (MGI) 13006 (Entrez Gene) Gene Tree Smc3 (Alliance of Genome Resources)	Chr19 48.13 cM	Chr19:53588827-53634262 (+) GRCm39	Cornelia de Lange syndrome 3	13006 (NCBI Gene Model) Q9CW03 (UniProt | EBI) NM_007790 (RefSeq)
rat	Smc3	RGD:62006 (Rat Genome Database) 29486 (Entrez Gene) Smc3 (Alliance of Genome Resources)	Chr1 q55			P97690 (UniProt | EBI) NM_031583 (RefSeq)
zebrafish	smc3	ZDB-GENE-030131-3196 (Zebrafish Model Organism Database) 324475 (Entrez Gene) smc3 (Alliance of Genome Resources)	Chr22			NP_999854 (RefSeq) NM_214689 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.