Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PIKFYVE	HGNC:23785 (HGNC) 200576 (Entrez Gene) 609414 (OMIM) PIKFYVE (Alliance of Genome Resources)	Chr2 q34	Chr2:208266056-208358746 (+) GRCh38	Fleck corneal dystrophy	Q9Y2I7 (UniProt | EBI) NM_001178000 (RefSeq)
mouse	Pikfyve	MGI:1335106 (MGI) 18711 (Entrez Gene) Gene Tree Pikfyve (Alliance of Genome Resources)	Chr1 32.94 cM	Chr1:65225842-65317854 (+) GRCm39	Crohn's disease	ENSMUSG00000025949 (Ensembl Gene Model) ENSMUSP00000095314 (Ensembl) ENSMUST00000097707 (Ensembl)
rat	Pikfyve	RGD:1592067 (Rat Genome Database) 316457 (Entrez Gene) Pikfyve (Alliance of Genome Resources)	Chr9 q32			NP_001414206 (RefSeq) NM_001427277 (RefSeq)
zebrafish	pikfyve	ZDB-GENE-030131-9636 (Zebrafish Model Organism Database) 337690 (Entrez Gene) pikfyve (Alliance of Genome Resources)	Chr9			NP_001120777 (RefSeq) NM_001127305 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.