Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NEK1	HGNC:7744 (HGNC) 4750 (Entrez Gene) 604588 (OMIM) NEK1 (Alliance of Genome Resources)	Chr4 q33	Chr4:169369704-169612632 (-) GRCh38	amyotrophic lateral sclerosis type 24 asphyxiating thoracic dystrophy orofaciodigital syndrome short-rib thoracic dysplasia 6 with or without polydactyly	Q96PY6 (UniProt | EBI) NM_001374421 (RefSeq)
mouse	Nek1	MGI:97303 (MGI) 18004 (Entrez Gene) Gene Tree Nek1 (Alliance of Genome Resources)	Chr8 30.91 cM	Chr8:61446229-61584380 (+) GRCm39	autosomal recessive polycystic kidney disease	ENSMUSG00000031644 (Ensembl Gene Model) ENSMUSP00000147809 (Ensembl) ENSMUST00000211672 (Ensembl)
rat	Nek1	RGD:1309375 (Rat Genome Database) 290705 (Entrez Gene) Nek1 (Alliance of Genome Resources)	Chr16 p12			NP_001099552 (RefSeq) NM_001106082 (RefSeq)
zebrafish	nek1	ZDB-GENE-040730-1 (Zebrafish Model Organism Database) 556002 (Entrez Gene) nek1 (Alliance of Genome Resources)	Chr20			XP_009292953 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.