Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TECTA	HGNC:11720 (HGNC) 7007 (Entrez Gene) 602574 (OMIM) TECTA (Alliance of Genome Resources)	Chr11 q23.3	Chr11:121101243-121191490 (+) GRCh38	autosomal dominant nonsyndromic deafness 12 autosomal recessive nonsyndromic deafness 21 sensorineural hearing loss	O75443 (UniProt | EBI) NM_005422 (RefSeq)
mouse	Tecta	MGI:109575 (MGI) 21683 (Entrez Gene) Gene Tree Tecta (Alliance of Genome Resources)	Chr9 23.63 cM	Chr9:42240915-42311225 (-) GRCm39	autosomal dominant nonsyndromic deafness 12	ENSMUSG00000037705 (Ensembl Gene Model) ENSMUSP00000040262 (Ensembl) ENSMUST00000042190 (Ensembl)
rat	Tecta	RGD:1309824 (Rat Genome Database) 300653 (Entrez Gene) Tecta (Alliance of Genome Resources)	Chr8 q22			NP_001100284 (RefSeq) NM_001106814 (RefSeq)
zebrafish	tecta	ZDB-GENE-110411-120 (Zebrafish Model Organism Database) 561355 (Entrez Gene) tecta (Alliance of Genome Resources)	Chr5			XP_017211866 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.