Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SYNE2	HGNC:17084 (HGNC) 23224 (Entrez Gene) 608442 (OMIM) SYNE2 (Alliance of Genome Resources)	Chr14 q23.2	Chr14:63761596-64226449 (+) GRCh38	autosomal dominant Emery-Dreifuss muscular dystrophy 5	Q8WXH0 (UniProt | EBI) NM_182912 (RefSeq)
mouse	Syne2	MGI:2449316 (MGI) 319565 (Entrez Gene) Gene Tree Syne2 (Alliance of Genome Resources)	Chr12 33.11 cM	Chr12:75865092-76157702 (+) GRCm39		319565 (NCBI Gene Model) Q6ZWQ0 (UniProt | EBI) NM_001005510 (RefSeq)
zebrafish	syne2a	ZDB-GENE-041001-109 (Zebrafish Model Organism Database) 559363 (Entrez Gene) syne2a (Alliance of Genome Resources)	Chr20			NP_001352259 (RefSeq) NM_001365330 (RefSeq)
	syne2b	ZDB-GENE-071218-5 (Zebrafish Model Organism Database) 559348 (Entrez Gene) syne2b (Alliance of Genome Resources)	Chr13			XP_021336559 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.