Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FYN	HGNC:4037 (HGNC) 2534 (Entrez Gene) 137025 (OMIM) FYN (Alliance of Genome Resources)	Chr6 q21	Chr6:111660332-111873452 (-) GRCh38	Alzheimer's disease schizophrenia	P06241 (UniProt | EBI) NM_001242779 (RefSeq)
mouse	Fyn	MGI:95602 (MGI) 14360 (Entrez Gene) Gene Tree Fyn (Alliance of Genome Resources)	Chr10 20.51 cM	Chr10:39245735-39441377 (+) GRCm39	skin disease skin squamous cell carcinoma	14360 (NCBI Gene Model) P39688 (UniProt | EBI) NM_001122893 (RefSeq)
rat	Fyn	RGD:2641 (Rat Genome Database) 25150 (Entrez Gene) Fyn (Alliance of Genome Resources)	Chr20 q12			Q62844 (UniProt | EBI) NM_012755 (RefSeq)
zebrafish	fyna	ZDB-GENE-030903-5 (Zebrafish Model Organism Database) 373872 (Entrez Gene) fyna (Alliance of Genome Resources)	Chr17			Q6EWH2 (UniProt | EBI) NM_001007286 (RefSeq)
	fynb	ZDB-GENE-050706-89 (Zebrafish Model Organism Database) 574422 (Entrez Gene) fynb (Alliance of Genome Resources)	Chr20			F1RDG9 (UniProt | EBI) NM_001029969 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.