Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AGXT2	HGNC:14412 (HGNC) 64902 (Entrez Gene) 612471 (OMIM) AGXT2 (Alliance of Genome Resources)	Chr5 p13.2	Chr5:34998101-35048135 (-) GRCh38	atrial fibrillation cerebral infarction congestive heart failure coronary artery disease hypertension intermittent claudication mild cognitive impairment	Q9BYV1 (UniProt | EBI) NM_031900 (RefSeq)
mouse	Agxt2	MGI:2146052 (MGI) 268782 (Entrez Gene) Gene Tree Agxt2 (Alliance of Genome Resources)	Chr15 5.35 cM	Chr15:10358618-10410239 (+) GRCm39		ENSMUSG00000089678 (Ensembl Gene Model) ENSMUSP00000022858 (Ensembl) ENSMUST00000022858 (Ensembl)
rat	Agxt2	RGD:621767 (Rat Genome Database) 83784 (Entrez Gene) Agxt2 (Alliance of Genome Resources)	Chr2 q16			Q64565 (UniProt | EBI) NM_031835 (RefSeq)
zebrafish	agxt2	ZDB-GENE-050913-100 (Zebrafish Model Organism Database) 619269 (Entrez Gene) agxt2 (Alliance of Genome Resources)	Chr21			NP_001028922 (RefSeq) NM_001033750 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.