Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL2RG	HGNC:6010 (HGNC) 3561 (Entrez Gene) 308380 (OMIM) IL2RG (Alliance of Genome Resources)	ChrX q13.1	ChrX:71107404-71112108 (-) GRCh38	combined T cell and B cell immunodeficiency severe combined immunodeficiency X-linked severe combined immunodeficiency	P31785 (UniProt | EBI) NM_000206 (RefSeq)
mouse	Il2rg	MGI:96551 (MGI) 16186 (Entrez Gene) Gene Tree Il2rg (Alliance of Genome Resources)	ChrX 43.9 cM	ChrX:100307991-100311861 (-) GRCm39		16186 (NCBI Gene Model) P34902 (UniProt | EBI) NM_013563 (RefSeq)
rat	Il2rg	RGD:621466 (Rat Genome Database) 140924 (Entrez Gene) Il2rg (Alliance of Genome Resources)	ChrX q22			NP_543165 (RefSeq) NM_080889 (RefSeq)
zebrafish	il2rga	ZDB-GENE-080402-1 (Zebrafish Model Organism Database) 796604 (Entrez Gene) il2rga (Alliance of Genome Resources)	Chr10			NP_001121743 (RefSeq) NM_001128271 (RefSeq)
	il2rgb	ZDB-GENE-080402-2 (Zebrafish Model Organism Database) 100144554 (Entrez Gene) il2rgb (Alliance of Genome Resources)	Chr14			NP_001116522 (RefSeq) NM_001123050 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.