Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SCARB2	HGNC:1665 (HGNC) 950 (Entrez Gene) 602257 (OMIM) SCARB2 (Alliance of Genome Resources)	Chr4 q21.1	Chr4:76158737-76234536 (-) GRCh38	progressive myoclonus epilepsy 4	Q14108 (UniProt | EBI) NM_001204255 (RefSeq)
mouse	Scarb2	MGI:1196458 (MGI) 12492 (Entrez Gene) Gene Tree Scarb2 (Alliance of Genome Resources)	Chr5 46.82 cM	Chr5:92589170-92653516 (-) GRCm39	progressive myoclonus epilepsy	12492 (NCBI Gene Model) O35114 (UniProt | EBI) NM_007644 (RefSeq)
rat	Scarb2	RGD:621882 (Rat Genome Database) 117106 (Entrez Gene) Scarb2 (Alliance of Genome Resources)	Chr14 p22			P27615 (UniProt | EBI) NM_054001 (RefSeq)
zebrafish	scarb2a	ZDB-GENE-020419-29 (Zebrafish Model Organism Database) 192340 (Entrez Gene) scarb2a (Alliance of Genome Resources)	Chr5			NP_775366 (RefSeq) NM_173259 (RefSeq)
	scarb2b	ZDB-GENE-170406-1 (Zebrafish Model Organism Database) 564077 (Entrez Gene) scarb2b (Alliance of Genome Resources)	ChrUN			XP_009299911 (RefSeq)
	scarb2c	ZDB-GENE-030131-5789 (Zebrafish Model Organism Database) 337532 (Entrez Gene) scarb2c (Alliance of Genome Resources)	Chr21			NP_001352071 (RefSeq) NM_001365142 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.