Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RGS5	HGNC:10001 (HGNC) 8490 (Entrez Gene) 603276 (OMIM) RGS5 (Alliance of Genome Resources)	Chr1 q23.3	Chr1:163111121-163321791 (-) GRCh38	colorectal adenocarcinoma essential hypertension	O15539 (UniProt | EBI) NM_001414478 (RefSeq)
mouse	Rgs5	MGI:1098434 (MGI) 19737 (Entrez Gene) Gene Tree Rgs5 (Alliance of Genome Resources)	Chr1 76.84 cM	Chr1:169483070-169523367 (+) GRCm39		19737 (NCBI Gene Model) O08850 (UniProt | EBI) NM_009063 (RefSeq)
rat	Rgs5	RGD:3568 (Rat Genome Database) 54294 (Entrez Gene) Rgs5 (Alliance of Genome Resources)	Chr13 q24			P49800 (UniProt | EBI) NM_019341 (RefSeq)
zebrafish	rgs5a	ZDB-GENE-030131-7570 (Zebrafish Model Organism Database) 573765 (Entrez Gene) rgs5a (Alliance of Genome Resources)	Chr6			NP_956256 (RefSeq) NM_199962 (RefSeq)
	rgs5b	ZDB-GENE-050417-359 (Zebrafish Model Organism Database) 550519 (Entrez Gene) rgs5b (Alliance of Genome Resources)	Chr2			NP_001017821 (RefSeq) NM_001017821 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.