Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HSD17B4	HGNC:5213 (HGNC) 3295 (Entrez Gene) 601860 (OMIM) HSD17B4 (Alliance of Genome Resources)	Chr5 q23.1	Chr5:119452465-119637199 (+) GRCh38	D-bifunctional protein deficiency Perrault syndrome Stiff-Person syndrome	P51659 (UniProt | EBI) NM_001374499 (RefSeq)
mouse	Hsd17b4	MGI:105089 (MGI) 15488 (Entrez Gene) Gene Tree Hsd17b4 (Alliance of Genome Resources)	Chr18 27.24 cM	Chr18:50261268-50329336 (+) GRCm39	D-bifunctional protein deficiency	ENSMUSG00000024507 (Ensembl Gene Model) ENSMUSP00000025385 (Ensembl) ENSMUST00000025385 (Ensembl)
rat	Hsd17b4	RGD:621806 (Rat Genome Database) 79244 (Entrez Gene) Hsd17b4 (Alliance of Genome Resources)	Chr18 q11			P97852 (UniProt | EBI) NM_024392 (RefSeq)
zebrafish	hsd17b4	ZDB-GENE-040421-1 (Zebrafish Model Organism Database) 393105 (Entrez Gene) hsd17b4 (Alliance of Genome Resources)	Chr8			NP_956430 (RefSeq) NM_200136 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.