Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GNB3	HGNC:4400 (HGNC) 2784 (Entrez Gene) 139130 (OMIM) GNB3 (Alliance of Genome Resources)	Chr12 p13.31	Chr12:6839954-6847393 (+) GRCh38	carotid artery disease congenital stationary night blindness 1H depressive disorder essential hypertension familial hyperlipidemia hypertension type 2 diabetes mellitus	P16520 (UniProt | EBI) NM_002075 (RefSeq)
mouse	Gnb3	MGI:95785 (MGI) 14695 (Entrez Gene) Gene Tree Gnb3 (Alliance of Genome Resources)	Chr6 59.17 cM	Chr6:124811203-124817238 (-) GRCm39		14695 (NCBI Gene Model) Q61011 (UniProt | EBI) NM_013530 (RefSeq)
rat	Gnb3	RGD:708344 (Rat Genome Database) 60449 (Entrez Gene) Gnb3 (Alliance of Genome Resources)	Chr4 q42			P52287 (UniProt | EBI) NM_021858 (RefSeq)
zebrafish	gnb3a	ZDB-GENE-040718-134 (Zebrafish Model Organism Database) 436710 (Entrez Gene) gnb3a (Alliance of Genome Resources)	Chr16			NP_001002437 (RefSeq) NM_001002437 (RefSeq)
	gnb3b	ZDB-GENE-040426-2280 (Zebrafish Model Organism Database) 406483 (Entrez Gene) gnb3b (Alliance of Genome Resources)	Chr19			NP_998367 (RefSeq) NM_213202 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.