Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PPARA	HGNC:9232 (HGNC) 5465 (Entrez Gene) 170998 (OMIM) PPARA (Alliance of Genome Resources)	Chr22 q13.31	Chr22:46150521-46243756 (+) GRCh38	Alzheimer's disease coronary artery disease hepatocellular carcinoma lipid metabolism disorder myocardial infarction	Q07869 (UniProt | EBI) NM_001393942 (RefSeq)
mouse	Ppara	MGI:104740 (MGI) 19013 (Entrez Gene) Gene Tree Ppara (Alliance of Genome Resources)	Chr15 40.42 cM	Chr15:85619184-85687020 (+) GRCm39	diabetes mellitus schizophrenia	ENSMUSG00000022383 (Ensembl Gene Model) ENSMUSP00000105050 (Ensembl) ENSMUST00000109423 (Ensembl)
rat	Ppara	RGD:3369 (Rat Genome Database) 25747 (Entrez Gene) Ppara (Alliance of Genome Resources)	Chr7 q34			P37230 (UniProt | EBI) NM_013196 (RefSeq)
zebrafish	pparaa	ZDB-GENE-041210-169 (Zebrafish Model Organism Database) 563298 (Entrez Gene) pparaa (Alliance of Genome Resources)	Chr4			NP_001154805 (RefSeq) NM_001161333 (RefSeq)
	pparab	ZDB-GENE-990415-211 (Zebrafish Model Organism Database) 557714 (Entrez Gene) pparab (Alliance of Genome Resources)	Chr25			NP_001096037 (RefSeq) NM_001102567 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.