Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DDR2	HGNC:2731 (HGNC) 4921 (Entrez Gene) 191311 (OMIM) DDR2 (Alliance of Genome Resources)	Chr1 q23.3	Chr1:162630863-162787405 (+) GRCh38	adenosquamous gallbladder carcinoma colorectal cancer gallbladder adenocarcinoma oral squamous cell carcinoma osteoarthritis spondylometaepiphyseal dysplasia, short limb-hand type stomach cancer	Q16832 (UniProt | EBI) NM_006182 (RefSeq)
mouse	Ddr2	MGI:1345277 (MGI) 18214 (Entrez Gene) Gene Tree Ddr2 (Alliance of Genome Resources)	Chr1 76.84 cM	Chr1:169799876-169938331 (-) GRCm39		ENSMUSG00000026674 (Ensembl Gene Model) ENSMUSP00000027985 (Ensembl) ENSMUST00000027985 (Ensembl)
rat	Ddr2	RGD:619855 (Rat Genome Database) 685781 (Entrez Gene) Ddr2 (Alliance of Genome Resources)	Chr13 q24			NP_113952 (RefSeq) NM_031764 (RefSeq)
zebrafish	ddr2a	ZDB-GENE-090316-2 (Zebrafish Model Organism Database) 556380 (Entrez Gene) ddr2a (Alliance of Genome Resources)	Chr6			XP_005166320 (RefSeq)
	ddr2b	ZDB-GENE-060503-361 (Zebrafish Model Organism Database) 559428 (Entrez Gene) ddr2b (Alliance of Genome Resources)	Chr2			XP_021322443 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.