Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SYN2	HGNC:11495 (HGNC) 6854 (Entrez Gene) 600755 (OMIM) SYN2 (Alliance of Genome Resources)	Chr3 p25.2	Chr3:12004388-12192032 (+) GRCh38	schizophrenia	Q92777 (UniProt | EBI) NM_003178 (RefSeq)
mouse	Syn2	MGI:103020 (MGI) 20965 (Entrez Gene) Gene Tree Syn2 (Alliance of Genome Resources)	Chr6 53.2 cM	Chr6:115111863-115258967 (+) GRCm39	autism spectrum disorder epilepsy	ENSMUSG00000009394 (Ensembl Gene Model) ENSMUSP00000009538 (Ensembl) ENSMUST00000009538 (Ensembl)
rat	Syn2	RGD:3798 (Rat Genome Database) 29179 (Entrez Gene) Syn2 (Alliance of Genome Resources)	Chr4 q42			Q63537 (UniProt | EBI) NM_001034020 (RefSeq)
zebrafish	syn2a	ZDB-GENE-040718-341 (Zebrafish Model Organism Database) 436870 (Entrez Gene) syn2a (Alliance of Genome Resources)	Chr23			NP_001002597 (RefSeq) NM_001002597 (RefSeq)
	syn2b	ZDB-GENE-051127-49 (Zebrafish Model Organism Database) 641578 (Entrez Gene) syn2b (Alliance of Genome Resources)	Chr11			NP_001314700 (RefSeq) NM_001327771 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.