Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PTGIS	HGNC:9603 (HGNC) 5740 (Entrez Gene) 601699 (OMIM) PTGIS (Alliance of Genome Resources)	Chr20 q13.13	Chr20:49503874-49568137 (-) GRCh38	carotid stenosis cerebral cavernous malformation 1 cerebral infarction colorectal adenoma essential hypertension hypertension limb ischemia myocardial infarction Parkinson's disease patent ductus arteriosus primary pulmonary hypertension pulmonary hypertension	Q16647 (UniProt | EBI) NM_000961 (RefSeq)
mouse	Ptgis	MGI:1097156 (MGI) 19223 (Entrez Gene) Gene Tree Ptgis (Alliance of Genome Resources)	Chr2 87.22 cM	Chr2:167033725-167082524 (-) GRCm39		ENSMUSG00000017969 (Ensembl Gene Model) ENSMUSP00000085357 (Ensembl) ENSMUST00000088041 (Ensembl)
rat	Ptgis	RGD:3438 (Rat Genome Database) 25527 (Entrez Gene) Ptgis (Alliance of Genome Resources)	Chr3 q42			Q62969 (UniProt | EBI) NM_031557 (RefSeq)
zebrafish	ptgis	ZDB-GENE-070116-1 (Zebrafish Model Organism Database) 559148 (Entrez Gene) ptgis (Alliance of Genome Resources)	Chr6			F1RE08 (UniProt | EBI) NM_001111160 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.