Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ARHGEF25	HGNC:30275 (HGNC) 115557 (Entrez Gene) 610215 (OMIM) ARHGEF25 (Alliance of Genome Resources)	Chr12 q13.3	Chr12:57610116-57617245 (+) GRCh38		Q86VW2 (UniProt | EBI) NM_001111270 (RefSeq)
mouse	Arhgef25	MGI:1277173 (MGI) 52666 (Entrez Gene) Gene Tree Arhgef25 (Alliance of Genome Resources)	Chr10 74.5 cM	Chr10:127018394-127025952 (-) GRCm39		ENSMUSG00000019467 (Ensembl Gene Model) ENSMUSP00000019611 (Ensembl) ENSMUST00000019611 (Ensembl)
rat	Arhgef25	RGD:735210 (Rat Genome Database) 314904 (Entrez Gene) Arhgef25 (Alliance of Genome Resources)	Chr7 q22			Q6P720 (UniProt | EBI) NM_199395 (RefSeq)
zebrafish	arhgef25a	ZDB-GENE-100728-4 (Zebrafish Model Organism Database) 100331456 (Entrez Gene) arhgef25a (Alliance of Genome Resources)	Chr23			XP_009295233 (RefSeq)
	arhgef25b	ZDB-GENE-080225-17 (Zebrafish Model Organism Database) 569561 (Entrez Gene) arhgef25b (Alliance of Genome Resources)	Chr6			XP_021332885 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.