Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CYP4A11	HGNC:2642 (HGNC) 1579 (Entrez Gene) 601310 (OMIM) CYP4A11 (Alliance of Genome Resources)	Chr1 p33	Chr1:46929177-46941484 (-) GRCh38	hypertension	Q02928 (UniProt | EBI) NM_000778 (RefSeq)
	CYP4A22	HGNC:20575 (HGNC) 284541 (Entrez Gene) 615341 (OMIM) CYP4A22 (Alliance of Genome Resources)	Chr1 p33	Chr1:47137435-47149727 (+) GRCh38		Q5TCH4 (UniProt | EBI) NM_001308102 (RefSeq)
mouse	Cyp4a14	MGI:1096550 (MGI) 13119 (Entrez Gene) Gene Tree Cyp4a14 (Alliance of Genome Resources)	Chr4 53.04 cM	Chr4:115343397-115353339 (-) GRCm39		ENSMUSG00000028715 (Ensembl Gene Model) ENSMUSP00000030487 (Ensembl) ENSMUST00000030487 (Ensembl)
rat	Cyp4a2	RGD:2479 (Rat Genome Database) 24306 (Entrez Gene) Cyp4a2 (Alliance of Genome Resources)	Chr5 q35			P20816 (UniProt | EBI) NM_001044770 (RefSeq)
	Cyp4a3	RGD:631356 (Rat Genome Database) 298423 (Entrez Gene) Cyp4a3 (Alliance of Genome Resources)	Chr5 q35			P20817 (UniProt | EBI) NM_175760 (RefSeq)
zebrafish	cyp4t8	ZDB-GENE-031219-3 (Zebrafish Model Organism Database) 387527 (Entrez Gene) cyp4t8 (Alliance of Genome Resources)	Chr16			NP_954686 (RefSeq) NM_199216 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.