Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CRTC1	HGNC:16062 (HGNC) 23373 (Entrez Gene) 607536 (OMIM) CRTC1 (Alliance of Genome Resources)	Chr19 p13.11	Chr19:18683678-18782333 (+) GRCh38		Q6UUV9 (UniProt | EBI) NM_015321 (RefSeq)
mouse	Crtc1	MGI:2142523 (MGI) 382056 (Entrez Gene) Gene Tree Crtc1 (Alliance of Genome Resources)	Chr8 34.15 cM	Chr8:70835005-70892229 (-) GRCm39	major depressive disorder	ENSMUSG00000003575 (Ensembl Gene Model) ENSMUSP00000075916 (Ensembl) ENSMUST00000076615 (Ensembl)
rat	Crtc1	RGD:1589158 (Rat Genome Database) 684527 (Entrez Gene) Crtc1 (Alliance of Genome Resources)	Chr16			Q157S1 (UniProt | EBI) NM_001047115 (RefSeq)
zebrafish	crtc1a	ZDB-GENE-061027-225 (Zebrafish Model Organism Database) 768293 (Entrez Gene) crtc1a (Alliance of Genome Resources)	Chr2			NP_001070925 (RefSeq) NM_001077457 (RefSeq)
	crtc1b	ZDB-GENE-041210-266 (Zebrafish Model Organism Database) 101886240 (Entrez Gene) crtc1b (Alliance of Genome Resources)	Chr11			NP_001352231 (RefSeq) NM_001365302 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.