Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SPTLC2	HGNC:11278 (HGNC) 9517 (Entrez Gene) 605713 (OMIM) SPTLC2 (Alliance of Genome Resources)	Chr14 q24.3	Chr14:77505997-77616637 (-) GRCh38	hereditary sensory and autonomic neuropathy type 1C	O15270 (UniProt | EBI) NM_004863 (RefSeq)
mouse	Sptlc2	MGI:108074 (MGI) 20773 (Entrez Gene) Gene Tree Sptlc2 (Alliance of Genome Resources)	Chr12 41.52 cM	Chr12:87351832-87435129 (-) GRCm39	psoriasis	20773 (NCBI Gene Model) P97363 (UniProt | EBI) NM_011479 (RefSeq)
rat	Sptlc2	RGD:1305447 (Rat Genome Database) 366697 (Entrez Gene) Sptlc2 (Alliance of Genome Resources)	Chr6 q31			Q3B7D2 (UniProt | EBI) NM_001037097 (RefSeq)
zebrafish	sptlc2a	ZDB-GENE-050522-23 (Zebrafish Model Organism Database) 553646 (Entrez Gene) sptlc2a (Alliance of Genome Resources)	Chr17			NP_001018455 (RefSeq) NM_001020619 (RefSeq)
	sptlc2b	ZDB-GENE-080305-8 (Zebrafish Model Organism Database) 557286 (Entrez Gene) sptlc2b (Alliance of Genome Resources)	Chr20			NP_001108213 (RefSeq) NM_001114741 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.