Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ANO5	HGNC:27337 (HGNC) 203859 (Entrez Gene) 608662 (OMIM) ANO5 (Alliance of Genome Resources)	Chr11 p14.3	Chr11:21782659-22283567 (+) GRCh38	autosomal recessive limb-girdle muscular dystrophy type 2L gnathodiaphyseal dysplasia isolated elevated serum creatine phosphokinase levels Miyoshi muscular dystrophy 3	Q75V66 (UniProt | EBI) NM_001142649 (RefSeq)
mouse	Ano5	MGI:3576659 (MGI) 233246 (Entrez Gene) Gene Tree Ano5 (Alliance of Genome Resources)	Chr7 32.76 cM	Chr7:51160777-51248457 (+) GRCm39	autosomal recessive limb-girdle muscular dystrophy type 2L gnathodiaphyseal dysplasia	ENSMUSG00000055489 (Ensembl Gene Model) ENSMUSP00000046884 (Ensembl) ENSMUST00000043944 (Ensembl)
rat	Ano5	RGD:1564265 (Rat Genome Database) 308637 (Entrez Gene) Ano5 (Alliance of Genome Resources)	Chr1 q22			NP_001419178 (RefSeq) NM_001432250 (RefSeq)
zebrafish	ano5a	ZDB-GENE-091013-2 (Zebrafish Model Organism Database) 100534737 (Entrez Gene) ano5a (Alliance of Genome Resources)	Chr25			XP_021326433 (RefSeq)
	ano5b	ZDB-GENE-061215-108 (Zebrafish Model Organism Database) 560102 (Entrez Gene) ano5b (Alliance of Genome Resources)	Chr7			NP_001073452 (RefSeq) NM_001079983 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.