Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ACTN3	HGNC:165 (HGNC) 89 (Entrez Gene) 102574 (OMIM) ACTN3 (Alliance of Genome Resources)	Chr11 q13.2	Chr11:66546395-66563334 (+) GRCh38		Q08043 (UniProt | EBI) NM_001104 (RefSeq)
mouse	Actn3	MGI:99678 (MGI) 11474 (Entrez Gene) Gene Tree Actn3 (Alliance of Genome Resources)	Chr19 4.12 cM	Chr19:4911244-4927937 (-) GRCm39		11474 (NCBI Gene Model) O88990 (UniProt | EBI) NM_013456 (RefSeq)
rat	Actn3	RGD:621792 (Rat Genome Database) 171009 (Entrez Gene) Actn3 (Alliance of Genome Resources)	Chr1 q43			NP_596915 (RefSeq) NM_133424 (RefSeq)
zebrafish	actn3a	ZDB-GENE-000329-9 (Zebrafish Model Organism Database) 58037 (Entrez Gene) actn3a (Alliance of Genome Resources)	Chr21			NP_571597 (RefSeq) NM_131522 (RefSeq)
	actn3b	ZDB-GENE-030131-2040 (Zebrafish Model Organism Database) 323320 (Entrez Gene) actn3b (Alliance of Genome Resources)	Chr7			NP_991107 (RefSeq) NM_205544 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.