Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FBXW4	HGNC:10847 (HGNC) 6468 (Entrez Gene) 608071 (OMIM) FBXW4 (Alliance of Genome Resources)	Chr10 q24.32	Chr10:101610664-101695295 (-) GRCh38		P57775 (UniProt | EBI) NM_022039 (RefSeq)
mouse	Fbxw4	MGI:1354698 (MGI) 30838 (Entrez Gene) Gene Tree Fbxw4 (Alliance of Genome Resources)	Chr19 38.75 cM	Chr19:45566693-45648751 (-) GRCm39		ENSMUSG00000040913 (Ensembl Gene Model) ENSMUSP00000036505 (Ensembl) ENSMUST00000046869 (Ensembl)
rat	Fbxw4	RGD:1306518 (Rat Genome Database) 309444 (Entrez Gene) Fbxw4 (Alliance of Genome Resources)	Chr1 q54			NP_001101070 (RefSeq) NM_001107600 (RefSeq)
zebrafish	fbxw4	ZDB-GENE-000516-1 (Zebrafish Model Organism Database) 58035 (Entrez Gene) fbxw4 (Alliance of Genome Resources)	Chr13			NP_571596 (RefSeq) NM_131521 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.