Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CLDN4	HGNC:2046 (HGNC) 1364 (Entrez Gene) 602909 (OMIM) CLDN4 (Alliance of Genome Resources)	Chr7 q11.23	Chr7:73799542-73832690 (+) GRCh38	ovarian cancer pancreatic cancer	O14493 (UniProt | EBI) NM_001305 (RefSeq)
mouse	Cldn13	MGI:1913102 (MGI) 57255 (Entrez Gene) Gene Tree Cldn13 (Alliance of Genome Resources)	Chr5 74.88 cM	Chr5:134943103-134944380 (-) GRCm39		ENSMUSG00000008843 (Ensembl Gene Model) ENSMUSP00000008987 (Ensembl) ENSMUST00000008987 (Ensembl)
zebrafish	cldna	ZDB-GENE-010328-1 (Zebrafish Model Organism Database) 81580 (Entrez Gene) cldna (Alliance of Genome Resources)	Chr15			NP_571837 (RefSeq) NM_131762 (RefSeq)
	cldnb	ZDB-GENE-010328-2 (Zebrafish Model Organism Database) 81581 (Entrez Gene) cldnb (Alliance of Genome Resources)	Chr21			NP_571838 (RefSeq) NM_131763 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.