Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ND6	HGNC:7462 (HGNC) 4541 (Entrez Gene) 516006 (OMIM) ND6 (Alliance of Genome Resources)	Chr	ChrMT:14149-14673 (-) GRCh38	Leber hereditary optic neuropathy Leigh disease spinal muscular atrophy with lower extremity predominant 2B	P03923 (UniProt | EBI)
mouse	mt-Nd6	MGI:102495 (MGI) 17722 (Entrez Gene) Gene Tree mt-Nd6 (Alliance of Genome Resources)	ChrMT Syntenic	ChrMT:13552-14070 (-) GRCm39	lactic acidosis Leber hereditary optic neuropathy	17722 (NCBI Gene Model) P03925 (UniProt | EBI) BC055066 (GenBank | ENA | DDBJ)
rat	ND6	RGD:620561 (Rat Genome Database) 26203 (Entrez Gene) ND6 (Alliance of Genome Resources)	ChrMT			P03926 (UniProt | EBI)
zebrafish	ND6	ZDB-GENE-011205-13 (Zebrafish Model Organism Database) 140536 (Entrez Gene) ND6 (Alliance of Genome Resources)	ChrMT			Q9MIX9 (UniProt | EBI)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.