PTGS2 Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/22/2024 MGI 6.24

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	PTGS2	HGNC:9605 (HGNC) 5743 (Entrez Gene) 600262 (OMIM) PTGS2 (Alliance of Genome Resources)	Chr1 q31.1	Chr1:186671791-186680922 (-) GRCh38	arteriosclerosis asthma avian influenza cardiovascular system disease chronic obstructive pulmonary disease cystic fibrosis esophagitis hepatocellular carcinoma idiopathic pulmonary fibrosis liver cirrhosis lung non-small cell carcinoma myocardial infarction osteoarthritis pancreatic cancer prostate cancer pulmonary fibrosis rheumatoid arthritis sarcoidosis urinary bladder cancer	P35354 (UniProt \| EBI) NM_000963 (RefSeq)
mouse	Ptgs2	MGI:97798 (MGI) 19225 (Entrez Gene) Gene Tree Ptgs2 (Alliance of Genome Resources)	Chr1 63.84 cM	Chr1:149975851-149983978 (+) GRCm39		19225 (NCBI Gene Model) Q05769 (UniProt \| EBI) NM_011198 (RefSeq)
rat	Ptgs2	RGD:620349 (Rat Genome Database) 29527 (Entrez Gene) Ptgs2 (Alliance of Genome Resources)	Chr13 q21			P35355 (UniProt \| EBI) NM_017232 (RefSeq)
zebrafish	ptgs2a	ZDB-GENE-020530-2 (Zebrafish Model Organism Database) 246227 (Entrez Gene) ptgs2a (Alliance of Genome Resources)	Chr2			NP_705943 (RefSeq) NM_153657 (RefSeq)
zebrafish	ptgs2b	ZDB-GENE-041014-323 (Zebrafish Model Organism Database) 559020 (Entrez Gene) ptgs2b (Alliance of Genome Resources)	Chr20			NP_001020675 (RefSeq) NM_001025504 (RefSeq)