Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ROBO4	HGNC:17985 (HGNC) 54538 (Entrez Gene) 607528 (OMIM) ROBO4 (Alliance of Genome Resources)	Chr11 q24.2	Chr11:124883691-124898500 (-) GRCh38	aortic valve disease 3	Q8WZ75 (UniProt | EBI) NM_019055 (RefSeq)
mouse	Robo4	MGI:1921394 (MGI) 74144 (Entrez Gene) Gene Tree Robo4 (Alliance of Genome Resources)	Chr9 20.76 cM	Chr9:37313198-37325319 (+) GRCm39		74144 (NCBI Gene Model) Q8C310 (UniProt | EBI) NM_001309390 (RefSeq)
zebrafish	robo4	ZDB-GENE-020809-1 (Zebrafish Model Organism Database) 560765 (Entrez Gene) robo4 (Alliance of Genome Resources)	Chr10			XP_005172767 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.