Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HP	HGNC:5141 (HGNC) 3240 (Entrez Gene) 140100 (OMIM) HP (Alliance of Genome Resources)	Chr16 q22.2	Chr16:72054505-72061055 (+) GRCh38	arteriosclerosis gout hemolytic anemia hyperglycemia hypertension myocardial infarction Plasmodium falciparum malaria pre-eclampsia pulmonary hypertension	P00738 (UniProt | EBI) NM_005143 (RefSeq)
	HPR	HGNC:5156 (HGNC) 3250 (Entrez Gene) 140210 (OMIM) HPR (Alliance of Genome Resources)	Chr16 q22.2	Chr16:72063148-72077246 (+) GRCh38		P00739 (UniProt | EBI) NM_001384360 (RefSeq)
mouse	Hp	MGI:96211 (MGI) 15439 (Entrez Gene) Gene Tree Hp (Alliance of Genome Resources)	Chr8 57.11 cM	Chr8:110301760-110305804 (-) GRCm39		15439 (NCBI Gene Model) Q61646 (UniProt | EBI) NM_017370 (RefSeq)
rat	Hp	RGD:2825 (Rat Genome Database) 24464 (Entrez Gene) Hp (Alliance of Genome Resources)	Chr19 q12			P06866 (UniProt | EBI) NM_012582 (RefSeq)
zebrafish	hp	ZDB-GENE-030131-1259 (Zebrafish Model Organism Database) 566096 (Entrez Gene) hp (Alliance of Genome Resources)	Chr7			NP_001352944 (RefSeq) NM_001366015 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.