Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TLK1	HGNC:11841 (HGNC) 9874 (Entrez Gene) 608438 (OMIM) TLK1 (Alliance of Genome Resources)	Chr2 q31.1	Chr2:170990823-171231314 (-) GRCh38		Q9UKI8 (UniProt | EBI) NM_001136554 (RefSeq)
mouse	Tlk1	MGI:2441683 (MGI) 228012 (Entrez Gene) Gene Tree Tlk1 (Alliance of Genome Resources)	Chr2 41.9 cM	Chr2:70542751-70656072 (-) GRCm39		ENSMUSG00000041997 (Ensembl Gene Model) ENSMUSP00000035961 (Ensembl) ENSMUST00000038584 (Ensembl)
rat	Tlk1	RGD:1310370 (Rat Genome Database) 311118 (Entrez Gene) Tlk1 (Alliance of Genome Resources)	Chr3 q22			NP_001381947 (RefSeq) NM_001395018 (RefSeq)
zebrafish	tlk1a	ZDB-GENE-071008-2 (Zebrafish Model Organism Database) 557765 (Entrez Gene) tlk1a (Alliance of Genome Resources)	Chr9			NP_001186653 (RefSeq) NM_001199724 (RefSeq)
	tlk1b	ZDB-GENE-030131-4933 (Zebrafish Model Organism Database) 326734 (Entrez Gene) tlk1b (Alliance of Genome Resources)	Chr6			Q90ZY6 (UniProt | EBI) NM_001024951 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.