Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CTSA	HGNC:9251 (HGNC) 5476 (Entrez Gene) 613111 (OMIM) CTSA (Alliance of Genome Resources)	Chr20 q13.12	Chr20:45890144-45898949 (+) GRCh38	galactosialidosis lysosomal storage disease	P10619 (UniProt | EBI) NM_001167594 (RefSeq)
mouse	Ctsa	MGI:97748 (MGI) 19025 (Entrez Gene) Gene Tree Ctsa (Alliance of Genome Resources)	Chr2 85.27 cM	Chr2:164674793-164682952 (+) GRCm39		ENSMUSG00000017760 (Ensembl Gene Model) ENSMUSP00000099381 (Ensembl) ENSMUST00000103092 (Ensembl)
rat	Ctsa	RGD:1309070 (Rat Genome Database) 296370 (Entrez Gene) Ctsa (Alliance of Genome Resources)	Chr3 q42			NP_001011959 (RefSeq) NM_001011959 (RefSeq)
zebrafish	ctsa	ZDB-GENE-030131-537 (Zebrafish Model Organism Database) 321818 (Entrez Gene) ctsa (Alliance of Genome Resources)	Chr6			NP_956844 (RefSeq) NM_200550 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.