Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HSPA4	HGNC:5237 (HGNC) 3308 (Entrez Gene) 601113 (OMIM) HSPA4 (Alliance of Genome Resources)	Chr5 q31.1	Chr5:133052013-133106449 (+) GRCh38	Chagas disease	P34932 (UniProt | EBI) NM_002154 (RefSeq)
mouse	Hspa4	MGI:1342292 (MGI) 15525 (Entrez Gene) Gene Tree Hspa4 (Alliance of Genome Resources)	Chr11 31.91 cM	Chr11:53150641-53191284 (-) GRCm39		ENSMUSG00000020361 (Ensembl Gene Model) ENSMUSP00000020630 (Ensembl) ENSMUST00000020630 (Ensembl)
rat	Hspa4	RGD:628878 (Rat Genome Database) 266759 (Entrez Gene) Hspa4 (Alliance of Genome Resources)	Chr10 q22			O88600 (UniProt | EBI) NM_153629 (RefSeq)
zebrafish	hspa4a	ZDB-GENE-040426-2832 (Zebrafish Model Organism Database) 335865 (Entrez Gene) hspa4a (Alliance of Genome Resources)	Chr21			NP_999881 (RefSeq) NM_214716 (RefSeq)
	hspa4b	ZDB-GENE-030131-6018 (Zebrafish Model Organism Database) 334086 (Entrez Gene) hspa4b (Alliance of Genome Resources)	Chr14			NP_956151 (RefSeq) NM_199857 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.