Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SORT1	HGNC:11186 (HGNC) 6272 (Entrez Gene) 602458 (OMIM) SORT1 (Alliance of Genome Resources)	Chr1 p21.3-p13.1	Chr1:109309568-109397918 (-) GRCh38	abdominal aortic aneurysm	Q99523 (UniProt | EBI) NM_001205228 (RefSeq)
mouse	Sort1	MGI:1338015 (MGI) 20661 (Entrez Gene) Gene Tree Sort1 (Alliance of Genome Resources)	Chr3 46.9 cM	Chr3:108191398-108268827 (+) GRCm39		ENSMUSG00000068747 (Ensembl Gene Model) ENSMUSP00000123564 (Ensembl) ENSMUST00000135636 (Ensembl)
rat	Sort1	RGD:619999 (Rat Genome Database) 83576 (Entrez Gene) Sort1 (Alliance of Genome Resources)	Chr2 q34			O54861 (UniProt | EBI) NM_031767 (RefSeq)
zebrafish	sort1a	ZDB-GENE-040426-2329 (Zebrafish Model Organism Database) 406511 (Entrez Gene) sort1a (Alliance of Genome Resources)	Chr11			Q6NUT7 (UniProt | EBI) NM_213230 (RefSeq)
	sort1b	ZDB-GENE-030131-7447 (Zebrafish Model Organism Database) 799153 (Entrez Gene) sort1b (Alliance of Genome Resources)	Chr8			NP_001119937 (RefSeq) NM_001126465 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.