Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CTH	HGNC:2501 (HGNC) 1491 (Entrez Gene) 607657 (OMIM) CTH (Alliance of Genome Resources)	Chr1 p31.1	Chr1:70411218-70439851 (+) GRCh38	amino acid metabolic disorder cystathioninuria	P32929 (UniProt | EBI) NM_001190463 (RefSeq)
mouse	Cth	MGI:1339968 (MGI) 107869 (Entrez Gene) Gene Tree Cth (Alliance of Genome Resources)	Chr3 81.55 cM	Chr3:157599885-157630714 (-) GRCm39	cystathioninuria	ENSMUSG00000028179 (Ensembl Gene Model) ENSMUSP00000113672 (Ensembl) ENSMUST00000118539 (Ensembl)
rat	Cth	RGD:2443 (Rat Genome Database) 24962 (Entrez Gene) Cth (Alliance of Genome Resources)	Chr2 q45			P18757 (UniProt | EBI) NM_017074 (RefSeq)
zebrafish	cth	ZDB-GENE-030131-774 (Zebrafish Model Organism Database) 322055 (Entrez Gene) cth (Alliance of Genome Resources)	Chr6			NP_997769 (RefSeq) NM_212604 (RefSeq)
	cthl	ZDB-GENE-040905-3 (Zebrafish Model Organism Database) 445818 (Entrez Gene) cthl (Alliance of Genome Resources)	Chr6			NP_001005400 (RefSeq) NM_001005400 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.