APOB Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	APOB	HGNC:603 (HGNC) 338 (Entrez Gene) 107730 (OMIM) APOB (Alliance of Genome Resources)	Chr2 p24.1	Chr2:21001429-21044073 (-) GRCh38	aortic valve stenosis arteriosclerosis bile duct cancer coronary artery disease diabetic retinopathy familial hypercholesterolemia familial hyperlipidemia familial hypobetalipoproteinemia 1 gallbladder cancer hypobetalipoproteinemia ovarian cancer sickle cell anemia type 2 diabetes mellitus	P04114 (UniProt \| EBI) NM_000384 (RefSeq)
mouse	Apob	MGI:88052 (MGI) 238055 (Entrez Gene) Gene Tree Apob (Alliance of Genome Resources)	Chr12 3.53 cM	Chr12:8027648-8066835 (+) GRCm39	familial hypobetalipoproteinemia 2	ENSMUSG00000020609 (Ensembl Gene Model) ENSMUSP00000036044 (Ensembl) ENSMUST00000037811 (Ensembl)
rat	Apob	RGD:2129 (Rat Genome Database) 54225 (Entrez Gene) Apob (Alliance of Genome Resources)	Chr6 q14			Q7TMA5 (UniProt \| EBI) NM_019287 (RefSeq)
zebrafish	apoba	ZDB-GENE-070702-4 (Zebrafish Model Organism Database) 566465 (Entrez Gene) apoba (Alliance of Genome Resources)	Chr17			XP_694827 (RefSeq)
	apobb.1	ZDB-GENE-030131-9732 (Zebrafish Model Organism Database) 321166 (Entrez Gene) apobb.1 (Alliance of Genome Resources)	Chr20			NP_001025233 (RefSeq) NM_001030062 (RefSeq)
	apobb.2	ZDB-GENE-070705-554 (Zebrafish Model Organism Database) 100330435 (Entrez Gene) apobb.2 (Alliance of Genome Resources)	Chr20			XP_002665852 (RefSeq)