Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TXNIP	HGNC:16952 (HGNC) 10628 (Entrez Gene) 606599 (OMIM) TXNIP (Alliance of Genome Resources)	Chr1 q21.1	Chr1:145992435-145996579 (-) GRCh38		Q9H3M7 (UniProt | EBI) NM_006472 (RefSeq)
mouse	Txnip	MGI:1889549 (MGI) 56338 (Entrez Gene) Gene Tree Txnip (Alliance of Genome Resources)	Chr3 41.93 cM	Chr3:96465273-96469173 (+) GRCm39	hepatocellular carcinoma Reye syndrome	56338 (NCBI Gene Model) Q8BG60 (UniProt | EBI) NM_001009935 (RefSeq)
rat	Txnip	RGD:620886 (Rat Genome Database) 117514 (Entrez Gene) Txnip (Alliance of Genome Resources)	Chr2 q34			Q5M7W1 (UniProt | EBI) NM_001008767 (RefSeq)
zebrafish	txnipa	ZDB-GENE-030804-10 (Zebrafish Model Organism Database) 368359 (Entrez Gene) txnipa (Alliance of Genome Resources)	Chr19			NP_956381 (RefSeq) NM_200087 (RefSeq)
	txnipb	ZDB-GENE-040917-1 (Zebrafish Model Organism Database) 448858 (Entrez Gene) txnipb (Alliance of Genome Resources)	Chr16			NP_001239433 (RefSeq) NM_001252504 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.