CYP46A1 Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	CYP46A1	HGNC:2641 (HGNC) 10858 (Entrez Gene) 604087 (OMIM) CYP46A1 (Alliance of Genome Resources)	Chr14 q32.2	Chr14:99684298-99727301 (+) GRCh38	Alzheimer's disease	Q9Y6A2 (UniProt \| EBI) NM_006668 (RefSeq)
mouse	Cyp46a1	MGI:1341877 (MGI) 13116 (Entrez Gene) Gene Tree Cyp46a1 (Alliance of Genome Resources)	Chr12 59.41 cM	Chr12:108300640-108328493 (+) GRCm39		ENSMUSG00000021259 (Ensembl Gene Model) ENSMUSP00000021684 (Ensembl) ENSMUST00000021684 (Ensembl)
rat	Cyp46a1	RGD:1306605 (Rat Genome Database) 362782 (Entrez Gene) Cyp46a1 (Alliance of Genome Resources)	Chr6 q32			NP_001386630 (RefSeq) NM_001399701 (RefSeq)
zebrafish	cyp46a1.1	ZDB-GENE-050522-464 (Zebrafish Model Organism Database) 553543 (Entrez Gene) cyp46a1.1 (Alliance of Genome Resources)	Chr20			NP_001018358 (RefSeq) NM_001020522 (RefSeq)
	cyp46a1.2	ZDB-GENE-040426-1184 (Zebrafish Model Organism Database) 393433 (Entrez Gene) cyp46a1.2 (Alliance of Genome Resources)	Chr20			NP_956755 (RefSeq) NM_200461 (RefSeq)
	cyp46a1.3	ZDB-GENE-060519-40 (Zebrafish Model Organism Database) 692332 (Entrez Gene) cyp46a1.3 (Alliance of Genome Resources)	Chr20			NP_001038763 (RefSeq) NM_001045298 (RefSeq)
	cyp46a1.4	ZDB-GENE-040426-1224 (Zebrafish Model Organism Database) 393451 (Entrez Gene) cyp46a1.4 (Alliance of Genome Resources)	Chr20			NP_956773 (RefSeq) NM_200479 (RefSeq)
	cyp46a1.5	ZDB-GENE-051120-33 (Zebrafish Model Organism Database) 641477 (Entrez Gene) cyp46a1.5 (Alliance of Genome Resources)	Chr20			NP_001032495 (RefSeq) NM_001037418 (RefSeq)