Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SMC1A	HGNC:11111 (HGNC) 8243 (Entrez Gene) 300040 (OMIM) SMC1A (Alliance of Genome Resources)	ChrX p11.22	ChrX:53374149-53422728 (-) GRCh38	congestive heart failure Cornelia de Lange syndrome 2 developmental and epileptic encephalopathy 85	Q14683 (UniProt | EBI) NM_001281463 (RefSeq)
mouse	Smc1a	MGI:1344345 (MGI) 24061 (Entrez Gene) Gene Tree Smc1a (Alliance of Genome Resources)	ChrX 68.46 cM	ChrX:150799386-150844969 (+) GRCm39		24061 (NCBI Gene Model) Q9CU62 (UniProt | EBI) NM_019710 (RefSeq)
rat	Smc1a	RGD:61991 (Rat Genome Database) 63996 (Entrez Gene) Smc1a (Alliance of Genome Resources)	ChrX q13			Q9Z1M9 (UniProt | EBI) NM_031683 (RefSeq)
zebrafish	smc1a	ZDB-GENE-090506-9 (Zebrafish Model Organism Database) 559665 (Entrez Gene) smc1a (Alliance of Genome Resources)	Chr23			NP_001155103 (RefSeq) NM_001161631 (RefSeq)
	smc1al	ZDB-GENE-040426-57 (Zebrafish Model Organism Database) 403060 (Entrez Gene) smc1al (Alliance of Genome Resources)	Chr23			NP_997975 (RefSeq) NM_212810 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.