Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	WDR45	HGNC:28912 (HGNC) 11152 (Entrez Gene) 300526 (OMIM) WDR45 (Alliance of Genome Resources)	ChrX p11.23	ChrX:49074433-49101178 (-) GRCh38	neurodegeneration with brain iron accumulation 5	Q9Y484 (UniProt | EBI) NM_001029896 (RefSeq)
mouse	Wdr45	MGI:1859606 (MGI) 54636 (Entrez Gene) Gene Tree Wdr45 (Alliance of Genome Resources)	ChrX 3.48 cM	ChrX:7588212-7594439 (+) GRCm39	neurodegeneration with brain iron accumulation 5	54636 (NCBI Gene Model) Q91VM3 (UniProt | EBI) NR_189681 (RefSeq)
rat	Wdr45	RGD:1359718 (Rat Genome Database) 302559 (Entrez Gene) Wdr45 (Alliance of Genome Resources)	ChrX q12			Q5U2Y0 (UniProt | EBI) NM_001398795 (RefSeq)
zebrafish	wdr45	ZDB-GENE-040426-990 (Zebrafish Model Organism Database) 393200 (Entrez Gene) wdr45 (Alliance of Genome Resources)	Chr10			Q7ZUX3 (UniProt | EBI) NM_200231 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.